Our research is funded in part by the National Natural Science Foundation of China, Beijing Natural Science Foundation, Beijing Nova Program, Beijing Nova Program Interdisciplinary Collaborative Project, Milstein Medical Asian American Partnership Foundation Fellowship Award in Translational Medicine, The Central Level Public Interest Program for Scientific Research Institute, PUMC Youth Fund & The Fundamental Research Funds for the Central Universities, CAMS Initiative Fund for Medical Sciences, the Distinguished Youth Foundation of Peking Union Medical College Hospital, the PUMCH Science Fund for Junior Faculty, and the National Key Research and Development Program of China.